Fmoc-(S)-3-Amino-4-(3,4-dichloro-phenyl)-butyric acid is an organic compound commonly used in solid-phase synthesis.
Nature:
-Appearance: White or off-white crystalline powder
-Molecular formula: C22H16Cl2NO4
-Molecular Weight: 434.27
-melting point: 155-158 ℃
-Soluble: Soluble in common organic solvents
Use:
Fmoc-(S)-3-Amino-4-(3,4-dichloro-phenyl)-butyric acid is widely used in solid phase synthesis as a starting material for the synthesis of proteins or peptide chains.
Preparation Method:
The preparation of Fmoc-(S)-3-Amino-4-(3,4-dichloro-phenyl)-butyric acid can be carried out by the following steps:
1. Fmoc-3-amino -4-(3,4-dichlorophenyl) butyric acid is combined with an active esterification reagent and activated under appropriate reaction conditions.
2. reacting the activated reagent with a suitable amino compound to produce the target compound.
3. The resulting product is crystallized and purified using an appropriate solvent and method.
Safety Information:
The safe use of Fmoc-(S)-3-Amino-4-(3,4-dichloro-phenyl)-butyric acid is subject to general laboratory safety practices. Wear appropriate protective equipment such as lab gloves and glasses during use. Avoid inhaling, chewing or touching the skin. If swallowed or skin contact occurs, seek medical advice immediately and show relevant information.